NC’s “Task Force Dragon” Returning Home From Eastern Europe

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Over 300 U.S. Army paratroopers from North Carolina have just touched down at Pope Army Airfield

The squad was part of ‘Task Force Dragon‘, a strategic assembly of various military forces commissioned with deterring Russian aggression in Eastern Europe’s NATO countries amid the ongoing war in Ukraine. The task force was established in South Eastern Poland, consisting of over 5,000 troops from the 82nd Airborne, 101st Airborne, and 16th Military Police Brigade.

Yesterday afternoon, in the hanger of Fort Bragg’s Green Ramp, hundreds of military family members held welcome home signs and anxiously waited to reunite with loved ones.

Fort Bragg said more paratroopers will be returning home from Europe in the coming weeks.

3rd CMPD Officer Shot Yesterday in NoDa

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Yesterday a CMPD officer was shot in the leg while responding to call of a shooting in an occupied dwelling.

According to the official report, the officer was rushed to the hospital with non-life-threatening injuries.

The officer did not return fire and the suspect is still at large.

This now marks the 3rd incident in a week where CMPD officers have faced gunfire during a call for service.

CMPD Chief Johnny Jennings released the following message about yesterday’s incident and the recent rise in officers being shot.

The Shark Week Blimp Is About To Fly Over Charlotte

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Discovery Channel’s legendary Shark Week is about to fly their massive Shark Week blimps over select cities in promotion of this year’s series.

There will be 2 blimps this year, one flying over select East Coast cities, and a second one flying over select West Coast cities. The East Coast blimp will be taking off on July 1st from Nashville, then will fly over Charlotte and Ocean City, MD on its way up to New York City.

Traveling approximately 250 miles per day, the East Coast blimp measures 128-feet long x 44ft high.

You can follow the blimps progress at Discovery.com/shark-week/blimp

The Future of Injectable Component Manufacturing: Trends and Innovations

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Injectable components, which include devices and containers used for drug delivery, play a vital role in the healthcare sector. With the ever-increasing demand for precision medicine, biologics, and personalized healthcare, the injectable component manufacturing industry is evolving rapidly. Manufacturers are striving to keep up with these changes, adopting new technologies, improving materials, and ensuring the highest standards of safety and efficiency. 

Injectable component manufacturer plays a pivotal role in the development and production of high-quality devices used for drug delivery. These manufacturers are responsible for ensuring that injectable components, such as syringes, vials, cartridges, and autoinjectors, meet rigorous standards for safety, performance, and patient satisfaction. The complexity of biologic drugs and the rise of personalized treatments demand that manufacturers not only produce components that are compatible with these therapies but also ensure that they are easy to use, cost-effective, and compliant with global regulatory standards.

Key Trends Shaping the Future of Injectable Component Manufacturing

1. Rise of Biologics and Biosimilars

Biologics, including monoclonal antibodies, gene therapies, and vaccines, represent a significant portion of new drug development. These complex therapies often require injectable delivery systems due to their nature (e.g., proteins, peptides, and nucleic acids). As biologics continue to gain popularity, the demand for injectable components that can safely and effectively deliver these drugs will increase.

Biosimilars, the follow-on versions of biologics, also require advanced injectable delivery systems. Manufacturers will need to develop components that ensure consistency, stability, and safety across batches of these highly complex drugs. This shift towards biologics and biosimilars will drive innovations in injectable components, such as the development of more sophisticated prefilled syringes, vials, and autoinjectors.

2. Personalized Medicine and Custom Injectable Devices

As personalized medicine continues to emerge, there will be a growing demand for tailored drug delivery solutions. Personalized treatments, which are customized based on a patient’s genetic makeup, disease state, and response to therapy, may require individualized injectable components. These could include specialized syringes, custom drug formulations, or devices with dosage adjustments tailored to each patient’s needs.

The future of injectable component manufacturing will likely see the introduction of smart devices that can monitor patient conditions and adjust drug delivery accordingly. These devices will incorporate features such as connectivity for remote monitoring, automatic dose adjustments, and data collection for better treatment outcomes. This trend will lead to innovations in both drug delivery devices and their integration with digital health technologies.

3. Prefilled Syringes and Autoinjectors: Growing Demand

Prefilled syringes (PFS) and autoinjectors have been gaining popularity due to their convenience and safety. Prefilled syringes are particularly beneficial for patients who need frequent injections, such as those with chronic conditions like rheumatoid arthritis, diabetes, and multiple sclerosis. These devices eliminate the need for manual filling, reducing the risk of contamination and dosing errors.

Autoinjectors, which are designed to allow patients to self-administer injections, are especially important for biologic therapies. As the number of chronic conditions requiring injectable biologics grows, the demand for these self-administration devices will rise. Manufacturers will need to focus on improving the ergonomics, ease of use, and reliability of these devices to ensure patient compliance and reduce the risk of incorrect use.

The future of prefilled syringes and autoinjectors will also involve innovations in the materials used, with manufacturers exploring options like biocompatible plastics and silicone-free components to improve device performance, especially in sensitive drug formulations.

4. Advancements in Materials Science

The materials used in injectable components are constantly evolving. As injectable therapies become more complex, manufacturers are focusing on developing materials that ensure compatibility with biologic and high-risk drugs. For example, glass and plastic components are commonly used in the production of vials, syringes, and cartridges. However, glass can be prone to breakage, while certain plastics may interact with the drug formulation, leading to issues like leaching or degradation.

Future innovations in materials science will likely focus on improving the biocompatibility and stability of injectable components. Manufacturers are exploring the use of new polymeric materials, such as polyethylene terephthalate (PET), which are less likely to react with drugs and can be sterilized more effectively. Additionally, coatings and surface treatments will continue to evolve to enhance drug compatibility and prevent issues like protein aggregation or oxidation.

5. Needle-Free Injection Systems

Needle-free injection systems are poised to become an important trend in injectable component manufacturing. These devices use a high-pressure jet to deliver medications through the skin without the need for needles. This method of drug delivery is especially appealing for patients who have a fear of needles or require frequent injections.

Needle-free devices are already being used for vaccines and some biologic therapies, and their potential to improve patient comfort and compliance is significant. However, these devices face challenges in terms of cost, efficiency, and suitability for different drug types. Future innovations will focus on enhancing the design and functionality of these systems to make them more affordable, reliable, and widely applicable.

6. Integration with Digital Health Technologies

As digital health technologies continue to evolve, there is a growing trend toward integrating injectable components with mobile apps, sensors, and cloud-based platforms. These systems enable real-time monitoring of medication usage, patient adherence, and drug efficacy. Smart syringes and autoinjectors equipped with sensors can track the amount of medication delivered, send notifications to healthcare providers, and ensure that patients follow their prescribed regimen.

The integration of digital health technologies into injectable components will not only improve patient outcomes but also provide valuable data for clinical trials, product development, and post-market surveillance. This trend will drive innovation in both the design of injectable devices and the broader healthcare ecosystem.

7. Sustainability and Eco-Friendly Practices

As sustainability becomes a top priority across industries, injectable component manufacturers are increasingly focusing on reducing their environmental impact. This includes efforts to minimize waste, use recyclable or biodegradable materials, and reduce the carbon footprint of manufacturing processes.

For example, some manufacturers are exploring reusable injectors and packaging solutions that reduce the need for single-use devices and packaging. Additionally, the shift toward green chemistry and environmentally friendly manufacturing techniques will play a key role in the future of injectable component manufacturing.

Innovations to Look Forward To

1. 3D Printing for Custom Injectable Devices

3D printing, or additive manufacturing, has the potential to revolutionize the production of custom injectable devices. Manufacturers can create prototypes quickly and efficiently, leading to faster product development and the ability to design devices tailored to individual patients’ needs. This technology could also allow for the creation of more intricate, patient-specific drug delivery devices with complex features, such as personalized dosing regimens or ergonomic designs.

2. Biodegradable Injectable Components

With an increasing focus on sustainability and reducing plastic waste, biodegradable components are likely to become more common in injectable devices. Materials that break down over time without leaving harmful residues are being researched, and these could be used for syringes, needles, and even packaging.

Conclusion

The future of injectable component manufacturing is marked by rapid innovation and the adoption of new technologies aimed at improving patient outcomes and enhancing drug delivery. From the rise of biologics and personalized medicine to advancements in materials science, digital health integration, and sustainability, injectable component manufacturers must adapt to an ever-changing landscape. As these trends continue to evolve, the industry will witness more efficient, safer, and more patient-friendly drug delivery systems, ultimately contributing to better healthcare worldwide. The future looks promising for injectable component manufacturers, with exciting innovations on the horizon that will shape the way we approach healthcare delivery.

Truist Commits $120M to Strengthening Black, Latinx and Women-Owned Small Businesses

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Yesterday, Bill Rogers, Chairman & CEO of Truist Financial Corporation, and Lynette Bell, President of Truist Foundation announced the bank’s $120 million commitment to strengthening and supporting Black, Latinx and women-owned small businesses across the country during an event at their Uptown Charlotte headquarters.  

As part of that overall commitment to small businesses, the company will make a $5 million national investment in Grameen America, including a $500,000 grant to Grameen America’s Charlotte portfolio, which will ultimately help generate $1.4 million in disbursements via 270 microloans to women entrepreneurs in one year. 

The bank’s new 2022 national commitment includes loans, investments and grants to organizations across the country, including:

  • Florida Community Loan Fund (FCLF) – $10 million
  • Local Initiatives Support Corporation (LISC) – $10 million
  • Empower the Change – $10 million
  • Grameen America – $5.5 million
  • Entrepreneur Backed Assets Fund (EBA) – $5 million
  • Minority Business Accelerator Fund (in conjunction with Cincinnati USA Regional Chamber) – $3 million
  • Asset Funders Network – $300,000
  • CommunityWorks – $300,000

Charlotte Sees #15 Largest Monthly Rent Increase

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Inflation is currently at its highest rate in 40 years, and rapidly rising housing costs are a key contributor. While the market has cooled slightly from last summer’s peaks, the national median rent has still jumped by 14% in the past year. And with spiking mortgage rates now sidelining potentially homebuyers, the coming months could bring additional competition for rentals amid a market that is already historically supply-constrained.
For the latest data, you can see the July Rent Report here, complete with median rent and price growth data through June 2022.
Highlights of the report include:
  • Rents in Charlotte increased 2.1% month-over-month in June, compared to a 1.3% increase nationally. Month-over-month growth in Charlotte ranks #15 among the nation’s 100 largest cities.
  • Year-over-year rent growth in Charlotte currently stands at 17.5%, compared to 10.6% at this time last year. Year-over-year growth in Charlotte ranks #21 among the nation’s 100 largest cities. Rents in Charlotte are up by 25.8% since the start of the pandemic in March 2020.
  • Median rents in Charlotte currently stand at $1338 for a 1-bedroom apartment and $1466 for a two-bedroom.

Ultrasonic Cleaning Myth Busting Facts You Need to Know

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I’ve heard everything about ultrasonic cleaning throughout the years. There’s a lot of

misinformation out there regarding the finest ultrasonic cleaners and what they can and can’t

perform. I’m not sure how or where it originated. This blog post will try to clarify some myths about ultrasonic cleaning.

“Ultrasonic cleaners can’t be used to clean Aluminium”

Whatever the origin of this urban legend is, it is NOT True. An ultrasonic cleaning machine is useful to clean a wide range of metals, as long as a suitable cleaning solution is used. Using a detergent that is safe for Aluminum, you can clean magnesium, titanium, brass, and Aluminum quickly and safely.

“Using an ultrasonic cleaner on a PCB may harm the solder joints“

When it comes to cleaning with ultrasonic devices, many people incorrectly assume that they

function by scrubbing the dirt off surfaces. This is not how this works. Ultrasonic machines create microscopic cavitation bubbles which remove contaminants from the part’s surface. PCBs may be cleaned effectively using ultrasonic cleaning. I am dispelling this common misconception.

“Ultrasonic cleaning is ineffective“

When the right chemicals, cleaning duration, and temperature parameters are applied, ultrasonic cleaning is highly effective in removing contaminants. Likely, some user started this myth by cleaning an item that was much too small for the machine they were using, or by using the incorrect chemicals. Whatever the regularly origin of the myth may be, this claim is just untrue, as hundreds of companies and sectors demonstrate.

“The longer an ultrasonic cleaner operates, the cleaner the parts will be“

Yes! It is true that the longer an ultrasonic cleaning process continues, the cleaner the

components get. The cleaner will achieve better results if run for 5 minutes rather than 3

minutes. As for how clean a component should be, the user has the last say. In certain cases, it may be “clean enough” after only three minutes, while in others, this may take five minutes. 

There is always some very small amount of contamination that will stay on the part and will not be removed by any cleaning efforts. If all dirt and debris have been removed after 15 minutes of ultrasonic cleaning, running the washer for an additional 5 minutes will no longer be required.

“Ultrasonic cleaners are not sterile“

False! Ultrasonic cleaners are now the sole means by which many dental, medical, and hospital facilities clean and sterilize their equipment. Every trace of bacteria, mold, and protein-based contamination can be removed from a tool using ultrasonic cleaning solutions. I’m sure my grandma was responsible for spreading this myth; she felt that nothing was clean until it had been immersed in boiling water. That’s out-of-date.

“Before using an ultrasonic cleaner, you must always clean the parts“

False. When using ultrasonic cleaning, there is no need to remove any contaminants from a

component before the start of the cleaning cycle.

Ultrasonic cleaners are fantastic cleaning tools because they operate with a virtually infinite number of materials, remove a wide variety of impurities, and accomplish both in a matter of minutes. Ultrasonic cleaning is only successful if the chemicals, temperature, and cycle duration are all just right. Once this is done, almost anything can be cleaned with ultrasonic waves without any risk or trouble.

Cashless Carowinds following a world trend

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Once upon a time, not having a few bucks in your pockets meant that a trip to Carowinds was impossible, but that’s not the case anymore. Yes, you still have to pay to get into the park and enjoy all the white-knuckle rollercoasters and rapid water slides, however, Carowinds has joined the digital revolution, meaning that you cannot use paper money in their venue to pay for your tickets for the park and food or drink.

So, all you need to take with you to Charlotte is your cell phone to use Apple Pay or Google Pay, or a credit or debit card with a contactless symbol. The fact that you don’t have to worry about taking cash to the park is a major bonus, considering all the cash you would need to carry to pay for tickets and other amenities. You also don’t have the concern of losing the cash by using your phone or card, something which 82% of Americans are appreciating all the more after turning to contactless payments. Carowinds has made the bold approach and it will be fascinating to see how this change works with customers. However, it is a growing trend across businesses in the United States, and ditching cash not only has benefits for the environment but also financially for all parties.

Digital payments are the main driving force behind transactions in the world of leisure and business in Charlotte and the United States as a whole, whether you’re buying groceries or eating out in a restaurant. The ability to tap the reader rather than having to draw out cash from an ATM saves not only valuable time but also provides security. It is a lot easier to keep track of your funds with digital payments, and that goes for both sides of the transaction. Life can be much simpler for businesses using digital payments rather than having to count out every nickel and dime from the cash register at the end of the day before filing that money away.

This has been noticed across the board, as casinos have also recognized the importance of offering a variety of payment methods for their users. With popular real money online casinos like Caesars and Betway Casino, users can can rest assured knowing that depositing and withdrawing money are as convenient as possible with well-known payment methods such as debit cards, PayPal, and Paynearme.

Apple Pay and Google Pay are also available to use for this medium and offer the same standard of protection you would find when entering card details. Payments with these methods can now be performed with a tap of your phone or watch. But it does not stop there, as some businesses now accept cryptocurrency as payment because of its popularity, particularly among the next generation. The world is changing at a rapid rate, and the old days of needing a few bucks in your pocket appear to be on the way out when visiting theme parks, eating out, and seemingly all leisure activities.

The ​First Case of Monkeypox Was Just Discovered in Mecklenburg County

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The first official case of Monkeypox has just been discovered in Mecklenburg County, according to NCDHHS.

The department noted that they’re working closely with the CDC and the patient’s healthcare providers to identify and reach out to individuals who may have been in contact with them while infectious.

“It is very important to be aware of the symptoms of monkeypox and to be vigilant. Individuals with concerning rashes should contact their healthcare provider,” said Meckleburg County Public Health Director Dr. Raynard Washington.  

Monkeypox infections normally occur through contact with the skin lesions or bodily fluids of infected animals or humans – including respiratory droplets – or through contact with materials that have been contaminated with the virus.

Symptoms of the virus include fever, chills, rash and aches, before worsening lesions develop.

North Carolinians Losing Interest in Crypto Following Recent Crash

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  • North Carolina workers would have each lost $1,866 if they had opted for their salaries to be partly paid in crypto.
  • Employees in Montana would have made the biggest losses following the crash.
  • Infographic showing crypto salary losses across America.
A recent survey by CouponBirds conducted prior to the recent crash in crypto currencies revealed that the average North Carolina employee would have liked to have received 29% of their monthly salary in a virtual currency. However, since the recent crash in crypto currencies, which has seen the value of Bitcoin drop by 57.01% since January, it appears North Carolina workers’ enthusiasm for crypto currencies has cooled.
The company, which is a provider of consumer information about real-time deals and savings, applied this percentage to the current value of Bitcoin and determined how much each employee would have hypothetically lost had they opted for partial crypto payments from January 2022.
The analysis revealed that each North Carolina employee would have made a significant loss on their crypto-based salary – $1,866.87 to be exact. To put it another way, an employee who opted to be paid only in US dollars would have earned $17,875.00 over a 6 month time period, compared to one who opted for a part crypto salary (29%), who would have earned $16,008.13 since January 2022.

When these figures were compared across the country, it appears employees in Montana would have made the biggest losses had they chosen to be paid in crypto. The average respondent wanted 69% of their monthly salary in the form of a cryptocurrency. However, this would have resulted in a $4,375.39 loss, as compared to sticking out a traditional salary payment. On the other hand, employees in Arkansas were the least enthusiastic about converting a portion of their salary to cybercash each month, saying they would consider receiving just 10% of their monthly payment in this form of currency, resulting in a comparatively less painful loss of $575.73 over the past six months.

When asked why they would prefer crypto salary payments, 1 in 5 workers said they believed they are more resistant to inflation. Cryptocurrency is often considered a safeguard against inflation, however, as current inflation remains high, and cryptocurrencies have crashed recently, they cannot be considered a long-term inflation-resistant asset.

The poll also found that 29% of employees said they would prefer to receive bonus payments or performance rewards in the form of NFTs. NFTs (non-fungible tokens), are digital assets are collectables created using blockchain technology. These digital assets are traded and bought online, with all linked transactions being recorded on the blockchain. While any person online can view the NFTs, only the buyer themselves has ownership authority.

Lastly, the survey revealed that 19% of respondents said they would be more likely to join a company if the work model was within the metaverse.