In a brain imaging study, a single 400 mg dose of CBD reduced anxiety in 10 people with seasonal affective disorder (SAD) works by reducing blood flow to part of the limbic system, which is often overactive in this type of disorder. The cannabinoid increased blood flow to another region that is important for cognition and motivation (the posterior cortex). More at https://biomdplus.com/cbd-oil-for-anxiety/
According to studies conducted on mice, CBD has an antidepressant effect. They found that CBD was as fast, potent, and long-lasting as the standard antidepressant. Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823358/
It appears that, with more research, the benefits of CBD may extend to individuals with different types of anxiety including panic attacks.
Consumers Should Check the Source of the CBD Oil
Look for a brand that is using “cannabidiol-rich” hemp.
There’s a big difference between CBD that comes from industrial hemp (the kind used for protein powders, clothing, and milk) and the hemp that is specifically grown to produce high-quality CBD products. You want to look for a brand that is using “can- nabidiol-rich” hemp. Otherwise, you risk purchasing a supplement that sounds effective but doesn’t deliver results. Plus, industrial hemp often lacks essential terpenes and secondary cannabinoids.
Look for a brand that is using “cannabidiol-rich” hemp.
Some brands try to save money by using toxic solvents that are dangerous to your health — such as propane, hexane, pentane and butane.
This is the “cheap and easy” extraction process, but it’s definitely not the kind of CBD you want. Instead, the more trustworthy brands are using organic, pharmaceutical-grade ethanol to process the CBD. The ethanol, which is a safe grain alcohol, is used to remove toxins and extra residue from the hemp.
This extraction process tends to produce the highest amount of cannabinoids and is considered to be the safest method of extracting that precious CBD.
To take it one step further, a few brands go above and beyond by using supercritical CO2 extraction. It sounds technical (and it is), but it’s basically using carbon dioxide under high pressure in an extremely cold environment to ensure the absolute purest form of CBD.
This CO2 extraction requires a lot of expensive, com- plex equipment, so most companies pass it up. But if you can find an affordable brand that invests in the technology, it is definitely worth it.
The final product contains fewer contaminants and a purer CBD oil. Win-win.
Be aware that some brands try to save money by using toxic solvents that are dangerous to your health — such as propane, hexane, pen- tane and butane. Please read all label carefully.
CBD Oil Lab Results
The CBD industry is still fairly young, so regulation is fairly limited. Companies should provide third-party lab test results to purity and safety.
As with any new industry, brand flood the market as quickly as possible. Some brands have thrown together a website, found a low-cost manufacturer, and started selling to eager buyers.
THIRD-PARTY TESTING: Make sure the CBD you are purchasing is backed by third-party testing. There is no way of confirming what’s in that product or if it’s safe to use without a lab report / Certificate of Analysis (COA). Only purchase from companies who have invested in unbiased testing from a third-party lab.
These independent labs exist to make sure that CBD oil is what it claims to be. They test for levels of CBD, THC, and ensure the product is free from harmful chemicals and impurities.
CONCERNED ABOUT PESTICIDES?
THC CONTENT: In the cannabis family, hemp is naturally extremely in THC and higher in CBD oil than its sibling, mar- ijuana. The way the law is written in the 2018 farm bill is that in order to be classified as hemp and legal to sell, a
It’s important to know whether or not the product contains harmful pesticides, fertilizers, growth hormones, or herbicides
hemp plant must contain less than 0.3% THC by volume.
that could induce negative side
Which means, CBD derived from hemp is no longer considered illegal by the DEA as long as it contains less than 0.3% THC. However, CBD derived from marijuana is still not legal on the federal level, nor are CBD oil products containing more than 0.3% THC.
effects. If the lab report shows any levels of these substances, you should give the product a “fail” status right away. How- ever, once the report confirms that your CBD oil is pesticide free, you can be sure it comes from pesticide-free grown hemp.
CBD Oil and Analgesic effects
Many studies suggest that cannabinoids may be a new class of “painkillers,” helping millions of people suffering from chronic pain. We have cannabinoid receptors throughout our bodies, but the CB1 type is very densely scattered along pathways responsible for brain, spine, and nerve pain. The second type, CB2, is more important for the immune system and acts on inflammation. Therefore, our internal cannabinoids and CBD can act on both of these pathways and balance pain and inflammation.
In an extensive analysis of 766 participants, cannabinoids strongly and safely reduced various types of chronic pain (pain from neuropathy, arthritis, fibromyalgia, HIV, and multiple sclerosis).
Another study with nearly 2,000 participants showed that the benefits of using cannabis-based drugs to fight pain outweigh any risks.
Moreover, the combination of CBD and THC reduced pain in several studies of patients with multiple sclerosis and chronic pain (66 and 189 participants, respectively). CBD was
The combination of CBD and THC offers promising results for postoperative and chronic pain, as well as pain related to cancer, rheumatoid arthritis, and neuropathy. However, it should be noted that by using only CBD, we still see benefits in comparison to synthetic cannabinoids and even to using it with THC because it is not a psychoactive substance. Many people want to avoid THC’s potential side-effects of paranoia and drowsiness.
CBD reduces pain in a different way than opioids do, though both substances alleviate it. The study showed that CBD oil did not affect the opioid pathways in mice. However, CBD reduced both chronic inflammation and neuropathic pain in rodents. Significantly, neither CBD nor THC appears to cause a long-term increase in tolerance (after two years), unlike opioids and most other painkillers, which require higher and higher doses to continue to work.
CBD Oil Dosage
CBD dosage may vary, but it usually ranges from 100 mg to even 3 g per day, depending on the target health problem.
For protecting the brain (e.g., Alzheimer’s disease), reducing inflammation, and addressing muscle spasms (multiple sclerosis), doses of 100 to 600 mg of CBD have been used in clinical trials. In some studies, patients took as much CBD oil as they needed to experience a reduction in pain or relief of muscle tone.
A dose of up to 800 mg per day was used to treat psychosis and schizophrenia.