Panthers Release 2025 NFL Schedule Featuring First Primetime Game Since 2023

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The Carolina Panthers released their full 2025 NFL regular season schedule Wednesday night, confirming a long-anticipated return to primetime action.

The Panthers will open the season on the road against the Jacksonville Jaguars on Sept. 7. Jacksonville, now led by new head coach Liam Cohen, will debut 2024 Heisman Trophy winner Travis Hunter, selected second overall in this year’s draft.

In Week 12, Carolina will make its first primetime appearance since 2023, facing the San Francisco 49ers on Monday Night Football in Santa Clara. That nationally televised matchup is set for Nov. 24 on ESPN.

The Panthers won’t get a break until Week 14, giving them one of the league’s latest bye weeks.

Here is the full 2025 Panthers schedule:

  • Week 1: at Jacksonville Jaguars — Sept. 7, 1 p.m. (FOX)

  • Week 2: at Arizona Cardinals — Sept. 14, 4:05 p.m. (CBS)

  • Week 3: vs. Atlanta Falcons — Sept. 21, 1 p.m. (FOX)

  • Week 4: at New England Patriots — Sept. 28, 1 p.m. (FOX)

  • Week 5: vs. Miami Dolphins — Oct. 5, 1 p.m. (FOX)

  • Week 6: vs. Dallas Cowboys — Oct. 12, 1 p.m. (FOX)

  • Week 7: at New York Jets — Oct. 19, 1 p.m. (FOX)

  • Week 8: vs. Buffalo Bills — Oct. 26, 1 p.m. (FOX)

  • Week 9: at Green Bay Packers — Nov. 2, 1 p.m. (FOX)

  • Week 10: vs. New Orleans Saints — Nov. 9, 1 p.m. (FOX)

  • Week 11: at Atlanta Falcons — Nov. 16, 1 p.m. (FOX)

  • Week 12: at San Francisco 49ers — Nov. 24, 8:15 p.m. (ESPN)

  • Week 13: vs. Los Angeles Rams — Nov. 30, 1 p.m. (FOX)

  • Week 14: Bye

  • Week 15: at New Orleans Saints — Dec. 14, 4:25 p.m. (FOX)

  • Week 16: vs. Tampa Bay Buccaneers — Dec. 21, 1 p.m. (FOX)

  • Week 17: vs. Seattle Seahawks — TBD

  • Week 18: at Tampa Bay Buccaneers — TBD

In spite of having easier schedule this year, it’s still unlikely that the Panthers will win any games this season.