NC Governor Josh Stein announced Monday that Genentech, a global biotech leader, will invest $700 million to build a new manufacturing facility in Holly Springs, located about two hours east of Charlotte.
The new plant will create at least 400 jobs with an average salary of $119,833, significantly higher than Wake County’s average wage of $76,643. The annual payroll impact is projected to exceed $50 million.
Stein made the announcement during the SelectUSA Investment Summit in Washington, D.C., highlighting the state’s growing role in life sciences and advanced manufacturing.
“World-class companies like Genentech recognize that North Carolina is a leading state for biotechnology,” said Governor Josh Stein in a press release. “These companies know that our life science workforce is ready to help them deliver their cutting-edge medicines to the world. We are proud to welcome Genentech to North Carolina.”
Headquartered in South San Francisco, Genentech is a member of the Switzerland-based Roche Group and is widely recognized as a biotechnology pioneer.
Major Economic Development Announcement 📢 Genentech, a member of the Roche Group based in Switzerland has announced plans to invest $700 million in #HollySprings to establish a new high-volume fill/finish manufacturing facility. Read more ➡️ https://t.co/PxT0oEKeki pic.twitter.com/dCb06JE23p
— Town of Holly Springs, NC (@ToHollySprings) May 12, 2025
The 700,000-square-foot facility will support high-volume fill-finish operations for Genentech’s current product line and future pipeline.
The project will be supported by a Job Development Investment Grant (JDIG) approved by the Economic Investment Committee. Over 12 years, it is expected to grow North Carolina’s economy by more than $3 billion. The JDIG allows for potential reimbursement of up to $9.8 million, contingent on Genentech creating 420 jobs and meeting performance benchmarks verified by the Departments of Commerce and Revenue.
Construction timelines and hiring dates for the project have not yet been announced.
